Dysplastic nevus - Nevus Displastik
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Dysplastic nevi ― Byopsi rekòmande pou moun Lwès yo.
References
Dysplastic nevus , ke yo rele tou yon nevus atipik oswa Clarks, te pwovoke deba nan dèrmatoloji ak dèrmatopatoloji. Doktè yo souvan byopsi mòl sa yo paske yo ka parèt anòmal epi ogmante enkyetid sou melanom.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi , ke yo rele tou atipik oswa Clark nevi, pafwa ka mennen nan melanom. Apeprè 36% nan melanom yo jwenn tou pre dysplastic nevi. Siy ke yon nevus dysplastic ka vire nan melanom gen ladan fòm inegal, plis chanjman pigman, oswa yon koulè gri. Kansè sa yo anjeneral rive nan yon laj ki pi piti (nan mitan ane trant yo) , yo ka plizyè, epi yo souvan sou kòf la. Jenetikman, dysplastic nevi yo ant nevi benign ak melanom. Sepandan, se sèlman 20% a 30% melanom ki soti nan nevi ki egziste deja. Piske pifò nevi pa vin melanom, anjeneral li pa rekòmande pou retire yo prevantif.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Yon melanom se yon kalite timè ki fòme lè melanosit, selil ki responsab koulè po a, vin kansè. Melanosit soti nan krèt neral la. Sa vle di ke melanom ka devlope pa sèlman sou po a, men tou nan lòt zòn kote selil krèt neral imigre, tankou aparèy gastwoentestinal la ak sèvo. Pousantaj siviv pou pasyan ki gen melanom nan etap bonè (etap 0) wo nan 97%, pandan ke li desann anpil nan apeprè 10% pou moun ki dyagnostike ak maladi nan etap avanse (etap IV) .
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Risk kansè
Jan yo wè nan moun ki Blan Ozetazini, moun ki gen nevi dysplastic gen yon risk pou tout lavi yo devlope melanom ki pi gran pase 10%. Nan lòt men an, moun ki pa gen okenn nevus dysplastic gen yon risk pou yo devlope melanom nan mwens pase 1%.
○ Prekosyon pou moun ki gen nevi displastik
Anjeneral, po a rekòmande pou anpeche melanom (pa idantifye nevi atipik ki ka retire) oswa pou deteksyon bonè nan timè ki egziste deja. Moun ki gen yon istwa pèsonèl oswa fanmi kansè po oswa plizyè nevi atipik ta dwe wè yon dèrmatològ omwen yon fwa pa ane pou asire yo pa devlope melanom.
Abrevyasyon [ABCDE] te itil pou ede founisè swen sante yo ak pwofàn sonje karakteristik kle yon melanom. Malerezman pou moun an mwayèn, anpil keratoz seboreik, kèk lentigo senil, e menm veri ka gen karakteristik [ABCDE], epi yo pa ka distenge ak yon melanom.
○ [ABCDE]
Asymmetrical: Lezyon po asimetri.
Border: Fwontyè blesi a iregilye.
Color: melanom anjeneral gen plizyè koulè iregilye.
Diameter: Nevi ki gen plis pase 6 mm gen plis chans pou yo melanom pase pi piti nevi.
Evolution: Evolisyon an (sa vle di chanjman) nan yon nevus oswa blesi ka endike ke blesi a ap vin malfezan.